Friday, March 1, 2013

Congo rebels clash near Goma after political chief sacked

KINSHASA (Reuters) - Heavy fighting broke out between two factions of Congo's M23 rebels near the eastern town of Goma on Thursday after one side said it sent men to arrest a leader of the other who is wanted by the International Criminal Court (ICC).

The M23 military commander said earlier that the M23 political coordinator Jean-Marie Runiga had been sacked, underlining infighting likely to undermine regional efforts to end two decades of conflict in central Africa.

The M23 rebellion is the latest uprising in Democratic Republic of Congo's mineral rich eastern borderlands. Last year the group inflicted a series of defeats on government forces, culminating in the brief seizure of the major town of Goma.

The emerging power struggle within rebel ranks will further damage efforts to resuscitate peace talks hosted by Uganda and may spur the Kinshasa government to push for a military solution to recurring rebellions in the east.

A Reuters witness in Goma said heavy weapons fire could be heard coming from the direction of rebel positions around Kibumba, some 25 km (14 miles) north of Goma.

"They attacked us so we reacted," said Colonel Seraphin Mirindi, spokesman for the M23 rebel faction loyal to Runiga.

Eight people were killed in clashes between M23 factions earlier this week.

In an earlier statement, the M23 military command said Runiga was ousted for stealing money and backing the rebel faction loyal to Bosco Ntaganda, a fighter wanted by the ICC on charges of killing civilians during a previous uprising.

The statement, signed by military commander Sultani Makenga, said Makenga would become the group's interim leader.

Runiga was unavailable for comment. He told Reuters on Wednesday there were no problems between himself and Makenga.

MOVE TO ARREST ICC SUSPECT

M23 spokesman and Makenga loyalist Colonel Vianney Kazarama said fighters had been dispatched to arrest Ntaganda, believed to be just 20 km (15 miles) north of Goma, on Thursday.

Mirindi, a pro-Ntaganda member of the group, warned: "We have the right to defend ourselves."

U.N. experts say Ntaganda has played a major command role within M23. This has been denied by the rebels.

"We'll see who emerges from this the winner," Thierry Vircoulon, Central Africa project director for the International Crisis Group think tank, said of the power struggle.

"I wouldn't say there's a good guy and a bad guy, but there's one who is more manageable, and the other who is wanted by the ICC. It's another argument for Kinshasa to perhaps go for the military option."

Goma's seizure in November embarrassed Congo's government and U.N. peacekeepers deployed to support Kinshasa's forces.

U.N. experts accused neighbouring Rwanda of backing the rebels. Kigali, which has repeatedly intervened in chaotic Congo's conflicts since Rwandan Hutu rebels sought refuge in the lawless east after the 1994 genocide, denied the charge.

Donors slashed millions of dollars in aid to Rwanda as a result. But there has been only slow progress since towards deploying a 4,000-strong international force to hunt down an array of rebel groups still operating in Congo.

Hundreds of thousands of people fled last year's violence, the latest in series of Tutsi-led rebellions whose roots can be traced to the aftermath of Rwanda's genocide and a cross-border web of ethnic, business and political interests.

African leaders signed a U.N.-mediated deal on Sunday paving the way for the deployment of military brigades.

But, having seen numerous other initiatives fail, there is scepticism whether the deal can remove the patchwork of rebel groups and pro-government militias that roam the east.

"The only situation that will make the government happy is the disappearance of politico-military movements like M23," said Congolese government spokesman Lambert Mende.

Source: http://news.yahoo.com/congo-rebels-sack-political-chief-splits-undermine-peace-101613436.html

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Mutation location is the key to prognosis

Feb. 28, 2013 ? The three most important factors in real estate are location, location, location, and the same might be said for mutations in the gene MECP2, said researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital in a report in the journal Cell.

"Where a mutation occurs can affect the severity of the symptoms of the disease," said Dr. Huda Zoghbi, professor of molecular and human genetics at BCM and director of the NRI. Zoghbi, corresponding author of the report, found the MECP2 gene in 1999 and confirmed that deficiency in the protein causes Rett syndrome, a post natal genetic disease that mainly affects girls.

Symptoms influenced by gene location

In the study, she and her colleagues relied on data from rare male patients with disruptions in MECP2 that showed that severity of symptoms could be influenced by the location of the gene mutation. The few boys with this disorder fell into two broad categories: Those who suffered severe brain disease and death before age 4 and those who lived for decades with symptoms similar to that of Rett or developmental delay and other disorders similar to those seen in autism.

Looking at the placement of the mutations in the boys, they hypothesized there was a distinct difference in symptoms seen in boys who had mutations at amino acid 270 in the protein and those who had mutations only slightly farther along, at amino acid 273. The protein is truncated or shorter in those with amino acid 270 mutations than those with the mutation at amino acid 273.

After Steven Baker, a graduate student in the Program in Developmental Biology at BCM, generated and characterized mice that had mutations at the two sites of the protein, he found that mice who had mutations at amino acid 273 lived longer and developed symptoms later than those mice who had mutations at amino acid 270 or those who lacked the MeCP2 protein all together (knock-out mice).

Disruption of topological feature

One reason for the differences could be that the mutation at amino acid 270 disrupts a key topological feature of the DNA -- an AT-Hook domain that is a DNA binding motif. By disrupting this domain, the mutation could affect the way the protein bind the DNA and make the already truncated protein much less effective.

"The participation of patients and their families with Rett researchers really helped us to key in on regions of MeCP2 that are critical for its function," said Baker, who is also an M.D./Ph.D. student in BCM's Medical Student Training Program.

The researchers propose a model for this DNA binding in which MeCP2 binds to sites across the genome. In some spots where this occurs, the protein manipulates the structure of the nearby chromatin.

Chromatin architectural factor

"We think that one function of MeCP2 (the protein associated with the gene) is to alter the architecture of chromatin (the mass of proteins and DNA found in the nucleus of the cell)," said Zoghbi, who is also Howard Hughes Medical Institute investigator.

Baker said, "The picture of MeCP2 as a chromatin architectural factor is emerging from the combined efforts of many laboratories. Understanding how MeCP2 modifies chromatin structure will ultimately allow us to understand why it is so important for neuronal health."

Others who took part in this work include Lin Chen, Angela Dawn Wilkins, Peng Yu and Olivier Lichtarge, all of BCM.

Funding for this work came from the Howard Hughes Medical Institute, the National Institute of Neurological Disease and Stroke (HD053862), and the Baylor College of Medicine Intellectual and Developmental Disability Research Center (F30NS066527).

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The above story is reprinted from materials provided by Baylor College of Medicine.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Steven?Andrew Baker, Lin Chen, Angela?Dawn Wilkins, Peng Yu, Olivier Lichtarge, Huda?Yahya Zoghbi. An AT-Hook Domain in MeCP2 Determines the Clinical Course of Rett Syndrome and Related Disorders. Cell, 2013; 152 (5): 984 DOI: 10.1016/j.cell.2013.01.038

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/76uIPhgyDTg/130228124130.htm

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Whistle-blower suit claimed Navy kickbacks in 2006

(AP) ? A recently unsealed whistle-blower lawsuit claims a former civilian Navy employee from Virginia and a now-defunct Navy contractor engaged in a bribery and kickback scheme going back to at least 2004.

The lawsuit, first filed in a federal court in Georgia in 2006, predates by more than four years criminal charges brought by federal prosecutors in Rhode Island in 2011 that allege a similar scheme by some of the same people cost the government $10 million.

A spokeswoman for the U.S. Department of Defense would not comment on why the contractor and Navy employee were allowed to continue their alleged criminal conduct for years after authorities were first alerted to it.

The lawsuit says the allegations were reported in May 2006 to the Defense Department and the U.S. attorney for northern Georgia. Other filings say the government was deciding whether to intervene in 2007 but had not yet completed an investigation.

A spokeswoman for the Department of Defense said she could not comment on investigations, while the U.S. attorney's office in Georgia referred questions to its counterpart office in Rhode Island. A spokesman in Rhode Island would not comment.

Both cases center on alleged wrongdoing by former civilian Navy employee Ralph Mariano and Anjan Dutta-Gupta, founder of the Navy contractor Advanced Solutions for Tomorrow, or ASFT, which had offices in Georgia and Rhode Island and has since gone out of business.

The criminal case and the whistle-blower suit say Mariano, who worked for the Naval Undersea Warfare Center, had power to add or refuse millions of dollars in payments to contractors and used that power to orchestrate a scheme in which he would approve payments to ASFT, which would then funnel some of the money back to him and others through shell corporations.

ASFT held $120 million in Navy contracts when the charges were first brought in February 2011. Mariano, of South Arlington, Va., remained in his job until 2011, according to court filings. He has pleaded not guilty in the criminal case. His lawyer, Robert Corrente, said his client had not yet been served by the lawsuit. He would not comment on the allegations contained in the lawsuit.

Dutta-Gupta and two others have pleaded guilty in federal court in Rhode Island in the criminal case. Dutta-Gupta admitted paying $8 million in bribes over more than a decade. His lawyer did not return a message seeking comment on the lawsuit.

Patrick Nagle, a former executive for ASFT, pleaded guilty to charges of conspiracy to commit bribery for signing off on false and inflated invoices that were submitted by subcontractors even though he knew the work had largely not been done. Another man, Russell Spencer, has admitted acting as a middleman for funneling kickbacks to Mariano through a company he owned. He pleaded guilty to conspiracy to commit bribery.

None of the three has been sentenced.

Mariano's father, Ralph Mariano Jr., of North Providence, R.I., and his girlfriend, Mary O'Rourke, a former executive at ASFT, have pleaded not guilty to the federal criminal charges. The younger Mariano and O'Rourke are charged with counts including conspiracy, theft of government property and wire fraud. Mariano Jr., who is in his 80s, is accused of tax evasion.

The whistle-blower suit was first brought in May 2006 by Rekha and Karan Vasudeva, who say they were involved in setting up a Roswell, Ga., company that was used to issue fictitious invoices to ASFT and a company owned by Spencer. It makes a number of other allegations against other people and companies, including about bid-rigging in U.S. Army contracts. An Army spokesman said he could not comment on matters under investigation or on open lawsuits.

While the criminal case accuses Mariano and Dutta-Gupta of wrongdoing back to 1996 and makes similar allegations to the 2006 whistle-blower suit, many of the specific claims in the cases are different.

The whistle-blower lawsuit was later filed in federal court in Rhode Island and amended in 2012 to include additional details based on the criminal case, including adding Spencer and Nagle as defendants. Several other people and companies are also named. The Vasudevas and their lawyers would not comment about the lawsuit.

The 2006 complaint was made in the form of a qui tam lawsuit under the federal False Claims Act, which allows private citizens to sue on the government's behalf. The action was sealed so that those who are named in it are not alerted to any investigation. It was unsealed by a federal judge in Providence in January at the request of prosecutors, who are required to alert defendants to evidence that exists before a criminal trial.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-02-28-Navy%20Kickbacks/id-37f512e62dc14873ba2e1cbba51e6808

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Amanda's Blog - Abide By These Quality Self Help Suggestions

Do you desire to live a better life? Keep reading for useful tips that can guide you along the path to becoming a new person.

Become aware of the distance you need to travel to achieve your self improvement goals. This is the first step to actually starting the journey of where you want to be. If you are unable to recognize this need, you will not be effective in developing yourself to your highest potential.

Do not be afraid to take risks in the pursuit of happiness. Many people get stuck in a zone that is comfortable so they do not risk failure or rejection, but the true risk is the loss of opportunities for personal growth. When you take a risk, you are showing yourself that you have courage, which is important to finding happiness.

When considering your own self improvement, focus on leadership. In this context, consider your sphere of influence to be where your leadership skills are applied. Look at your journey of leadership. What events have you been most impacted by in your life? How did these people and events change you as a person? When you work with a group, what attributes do you tend to rely on? By considering these questions, you can determine how to fit into a team-related setting.

A good self improvement plan has a physical health component. It is vital that you maintain motivation to eat well and exercise regularly. If you make your health the priority, you will likely feel your best, which makes contributing to the different aspects of life easier.

Each day should be an opportunity to top the previous day?s accomplishments. Push yourself to achieve growth that is constant and unwavering. Push yourself to do something better today than you did the day before.

Focus on changing just one thing about yourself at any given time. While you may want to change a number of things about yourself, by focusing on improving one thing at a time, there?s a better chance of you being successful. This means you will be able to maintain the changes as you turn them into habits as habits take time to stick.

Come up with a little pep talk for yourself. On a postcard, write down all of your best qualities. Keep the card in your purse or wallet, and pull it out every time you feel depressed and defeated or have a negative thought about yourself. You might even consider recording the mantra in your own voice, so that you can play it back at any time. ?Why would I want to do this??, you may be asking.

Do not overdo it when you are trying to achieve your self improvement goal. Although striving may be what fuels your accomplishments, you need to know when you are exceeding your own boundaries. You have to keep your body in mind when you are trying to accomplish something. Ignoring the needs of your body is guaranteed to set you back when you are trying to improve.

As you?ve just read, it?s not as frightening to better your life as you may think. If you are able to take control of your life and improve yourself, you will see a huge improvement in your quality of life.

Source: http://suppwapattu.edublogs.org/2013/02/28/abide-by-these-quality-self-help-suggestions/

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UN appeals court acquits ex-Serb military chief

THE HAGUE, Netherlands (AP) ? In a stunning reversal, U.N. appeals judges on Thursday acquitted the former chief of the Yugoslav National Army of aiding and abetting atrocities by rebel Serbs, including the Srebrenica massacre, by providing them with military aid during the Balkan wars.

Gen. Momcilo Perisic, a former close ally of ex-Yugoslav President Slobodan Milosevic, had been sentenced to 27 years in 2011 after being convicted of crimes including murder, inhumane acts and persecution. The judges ordered him freed immediately.

The judgment is a rare victory for Serbs at the Yugoslav war crimes tribunal, where most of the convicted suspects have been rebel Serbs in Bosnia and Croatia. It also supported Belgrade's often-stated assertion that it did not deliberately assist in Bosnian Serb atrocities and underscores how hard it is for international courts to prosecute senior officials seen as pulling the strings but not acting directly.

The court's most ambitious attempt to link Belgrade to Balkan war atrocities ended inconclusively when Milosevic died of a heart attack in his cell in The Hague in 2006 before a verdict could be reached in his trial for fomenting violence throughout the region as the former Yugoslavia crumbled.

While linking senior officials in one country to crimes by rebels in another is difficult, it can be done.

Another high-profile case that played out in a different Hague courtroom, the prosecution of Charles Taylor, saw the former Liberian president convicted of aiding and abetting rebels in neighboring Sierra Leone during that African nation's brutal civil war. Taylor has appealed his conviction and 50-year sentence.

Perisic, wearing a dark suit and tie, looked down and raised his eyebrows as Presiding Judge Theodor Meron said his convictions were being overturned in a 4-1 ruling by the five-judge appeals panel.

His acquittal on appeal is final and cannot be further appealed. Prosecutors could not immediately be reached for comment.

It has long been known that Belgrade provided arms and other equipment to Bosnian Serb forces, but Meron said the aid was for the Bosnian Serb "war effort" and prosecutors failed to prove it was given with the "specific intent" for forces led by Bosnian Serb military chief Gen. Ratko Mladic to commit crimes.

The Muslim Bosniak member of Bosnia's three-man presidency, Bakir Izetbegovic, said he was stunned by the ruling.

"So the side that was helping the Bosnian Serb army is not guilty of the crimes they had committed," he said. "But it lasted for years; if they did not know about the crimes at the start of the war, they knew about them in 1993, in 1994 and they continued to help."

Perisic's original conviction marked the first time the U.N. court had found a civilian or military officer from Serbia guilty of war crimes in Bosnia, and was seen as highlighting the Yugoslav army's far-reaching support for Serb forces in both Bosnia and Croatia.

Mladic, originally an officer in the Yugoslav army, is on trial in the same court on charges including genocide for allegedly masterminding the 1995 Srebrenica massacre in which some 8,000 Muslim men were murdered by Bosnian Serb forces in Europe's worst massacre since World War II.

Meron said Perisic's aid to Bosnian Serb forces "was remote to the relevant crimes" committed by rebel Serbs in Bosnia.

But Meron added a note of caution for leaders who would commit crimes through proxy forces.

"This conclusion should in no way be interpreted as enabling military leaders to deflect criminal liability by subcontracting the commission of criminal acts," he said.

In Belgrade, Serbia's deputy war crimes prosecutor Bruno Vekaric praised Perisic's acquittal, "most of all because the council of judges did not find a link between the Yugoslav army and the war crimes that took place in the former Yugoslavia, and because it found that Gen. Perisic acted in accordance with the rules of war."

In Bosnia, there was dismay among survivors of the Srebrenica massacre who watched the ruling on television.

"What did we believe in? We had faith in The Hague tribunal, we believed in justice, but there is no justice," survivor Suhra Sinanovic said.

In a landmark 2007 ruling, the U.N.'s highest judicial organ, the International Court of Justice, also cleared Serbia of genocide in Bosnia, but said the country's former government should have stopped the 1995 slaughter of some 8,000 Muslims in Srebrenica.

The International Court of Justice is a separate court from the tribunal that acquitted Perisic.

Perisic also was acquitted Thursday of failing to punish rebel Serbs in Croatia who shelled the capital Zagreb in May 1995.

Perisic was Serbia's military chief until 1998 ? three years after the Bosnian and Croatian wars ended. He turned against Milosevic after the Bosnian war and warned Milosevic's regime against fomenting conflict in Kosovo, where fighting erupted after he left his post.

In Bosnia, another Srebrenica survivor, Zijad Smajlovic, insisted that the court had enough evidence to convict Perisic.

"All human and technical resources of the Yugoslav Army were used in perpetration of war crimes and genocide in Bosnia," Smajlovic said. "Not only in Srebrenica, but in Bosnia in general."

____

Associated Press writers Jovana Gec in Belgrade, Serbia, and Sabina Niksic and Vojislav Stjepanovic in Sarajevo, Bosnia, contributed.

____

Follow Mike Corder on Twitter (at)mikecorder

Source: http://news.yahoo.com/un-appeals-court-acquits-ex-serb-military-chief-163412210.html

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Medicare paid $5.1B for poor nursing home care

(AP) ? Medicare paid billions in taxpayer dollars to nursing homes nationwide that were not meeting basic requirements to look after their residents, government investigators have found.

The report, released Thursday by the Department of Health and Human Services' inspector general, said Medicare paid about $5.1 billion for patients to stay in skilled nursing facilities that failed to meet federal quality of care rules in 2009, in some cases resulting in dangerous and neglectful conditions.

One out of every three times patients wound up in nursing homes that year, they landed in facilities that failed to follow basic care requirements laid out by the federal agency that administers Medicare, investigators estimated.

By law, nursing homes need to write up care plans specially tailored for each resident, so doctors, nurses, therapists and all other caregivers are on the same page about how to help residents reach the highest possible levels of physical, mental and psychological well-being.

Not only are residents often going without the crucial help they need, but the government could be spending taxpayer money on facilities that could endanger people's health, the report concluded. The findings come as concerns about health care quality and cost are garnering heightened attention as the Obama administration implements the nation's sweeping health care overhaul.

"These findings raise concerns about what Medicare is paying for," the report said.

Investigators estimate that in one out of five stays, patients' health problems weren't addressed in the care plans, falling far short of government directives. For example, one home made no plans to monitor a patient's use of two anti-psychotic drugs and one depression medication, even though the drugs could have serious side effects.

In other cases, residents got therapy they didn't need, which the report said was in the nursing homes' financial interest because they would be reimbursed at a higher rate by Medicare.

In one example, a patient kept getting physical and occupational therapy even though the care plan said all the health goals had been met, the report said.

The Office of Inspector General's report was based on medical records from 190 patient visits to nursing homes in 42 states that lasted at least three weeks, which investigators said gave them a statistically valid sample of Medicare beneficiaries' experiences in skilled nursing facilities.

That sample represents about 1.1 million patient visits to nursing homes nationwide in 2009, the most recent year for which data was available, according to the review.

Overall, the review raises questions about whether the system is allowing homes to get paid for poor quality services that may be harming residents, investigators said, and recommended that the Centers for Medicare & Medicaid Services tie payments to homes' abilities to meet basic care requirements. The report also recommended that the agency strengthen its regulations and ramp up its oversight. The review did not name individual homes, nor did it estimate the number of patients who had been mistreated, but instead looked at the overall number of stays in which problems arose.

In response, the agency agreed that it should consider tying Medicare reimbursements to homes' provision of good care. CMS also said in written comments that it is reviewing its own regulations to improve enforcement at the homes.

"Medicare has made significant changes to the way we pay providers thanks to the health care law, to reward better quality care," Medicare spokesman Brian Cook said in a statement to AP. "We are taking steps to make sure these facilities have the resources to improve the quality of their care, and make sure Medicare is paying for the quality of care that beneficiaries are entitled to."

CMS hires state-level agencies to survey the homes and make sure they are complying with federal law, and can require correction plans, deny payment or end a contract with a home if major deficiencies come to light. The agency also said it would follow up on potential enforcement at the homes featured in the report.

Greg Crist, a Washington-based spokeswoman for the American Health Care Association, which represents the largest share of skilled nursing facilities nationwide, said overall nursing home operators are well regulated and follow federal guidelines but added that he could not fully comment on the report's conclusions without having had the chance to read it.

"Our members begin every treatment with the individual's personal health needs at the forefront. This is a hands-on process, involving doctors and even family members in an effort to enhance the health outcome of the patient," Crist said.

Virginia Fichera, who has relatives in two nursing homes in New York, said she would welcome a greater push for accountability at skilled nursing facilities.

"Once you're in a nursing home, if things don't go right, you're really a prisoner," said Fichera, a retired professor in Sterling, NY. "As a concerned relative, you just want to know the care is good, and if there are problems, why they are happening and when they'll be fixed."

Once residents are ready to go back home or transfer to another facility, federal law also requires that the homes write special plans to make sure patients are safely discharged.

Investigators found the homes didn't always do what was needed to ensure a smooth transition.

In nearly one-third of cases, facilities also did not provide enough information when the patient moved to another setting, the report found.

___

On the Web:

The OIG report: http://1.usa.gov/VaztQm

The Medicare nursing home database: http://www.medicare.gov/NursingHomeCompare/search.aspx?bhcp=1&AspxAutoDetectCookieSupport=1

___

Follow Garance Burke on Twitter at ?http://twitter.com/garanceburke.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/bbd825583c8542898e6fa7d440b9febc/Article_2013-02-28-Nursing%20Homes-Poor%20Care/id-2429e3a092e643079bc13ea7dfc520ac

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Was It Worth It Tracks Your Past Projects, the Money You Spent, Fun You Had, and More

Was It Worth It Tracks Your Past Projects, the Money You Spent, Fun You Had, and MoreiOS: If you're the type to take on a lot of different side projects, it's easy to forget about their details. Was It Worth It is an app that tracks your projects, their cost, how much fun you had with them, and any knowledge you might have gained.

Was It Worth It is aimed more toward freelancers who take on a lot of different projects, but it's useful for anyone who DIYs their way through a lot of jobs. The goal is to keep track of what projects are worth it to you. It does this by letting you enter in how much money you made (or lost), the amount of fun you had working on it, and the knowledge you gained. From there, Was It Worth It breaks your projects down into a nice graph so you can quickly see if that work is worth doing again. It's simple, easy to use, and if you're the type who has a lot of projects on the table at once, Was It Worth It is helpful to keep track of it all.

Was It Worth It (free) | iTunes App Store via Swiss Miss

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/y7ioPHqZ4jA/was-it-worth-it-tracks-your-past-projects-the-money-you-spent-fun-you-had-and-more

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